Nucleated red blood cells, critical illness survivors and postdischarge outcomes: a cohort study

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Nucleated red blood cells, critical illness survivors and postdischarge outcomes: a cohort study

BACKGROUND Little is known about risk factors associated with out-of-hospital outcomes in survivors of critical illness. We hypothesized that the presence of nucleated red blood cells in patients who survived critical care would be associated with adverse outcomes following hospital discharge. METHODS We performed a two-center observational cohort study of patients treated in medical and surg...

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A study protocol for an observational cohort investigating COGnitive outcomes and WELLness in survivors of critical illness: the COGWELL study

INTRODUCTION Up to 9 out of 10 intensive care unit (ICU) survivors will suffer some degree of cognitive impairment at hospital discharge and approximately half will have decrements that persist for years. The mechanisms for this newly acquired brain injury are poorly understood. The purpose of this study is to describe the prevalence of sleep abnormalities and their association with cognitive i...

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Nucleated red blood cells in the blood of medical intensive care patients indicate increased mortality risk: a prospective cohort study

INTRODUCTION In critically ill patients, the appearance of nucleated red blood cells (NRBCs) in blood is associated with a variety of severe diseases. Generally, when NRBCs are detected in the patients' blood, the prognosis is poor. METHODS In a prospective study, the detection of NRBCs was used for a daily monitoring of 383 medical intensive care patients. RESULTS The incidence of NRBCs in...

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Nucleated red blood cells in the fetus and newborn.

Although nucleated red blood cells (nRBCs) are rarely found circulating in older children, they are commonly seen in the blood of newborns. They are primarily produced in the fetal bone marrow in response to erythropoietin and are stored in the marrow as precursors to reticulocytes and mature erythrocytes. Many acute and chronic stimuli cause increases in the number of circulating nRBCs from ei...

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Nucleated Red Blood Cells as Predictors of All-Cause Mortality in Cardiac Intensive Care Unit Patients: A Prospective Cohort Study

BACKGROUND The presence of nucleated red blood cells (NRBCs) in the peripheral blood of critically ill patients is associated with a poorer prognosis, though data on cardiovascular critical care patients is lacking. The aim of the present study was to assess the role of NRBCs as a predictor of intensive care unit (ICU) and in hospital all-cause mortality among cardiologic patients. METHODS NR...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2017

ISSN: 1364-8535

DOI: 10.1186/s13054-017-1724-z